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More →OpenAI Buys Orchestra Bio to Put AI Agents in Charge of Drug Development Grunt Work
OpenAI has bought Orchestra Bio, a San Francisco startup whose AI agents help drug companies keep sprawling development programs on schedule, the ChatGPT maker <a href="https://openai.com/index/openai-to-acquire-orchestra-bio/" target="_blank" rel="nofollow external noopener" class="sc-adb616fe-0 dJryYS">>announced Tuesday</a>. “Our goal is to help scientists make discoveries and manage the work needed to turn them into treatments that reach patients sooner,” OpenAI said in the announcement. Orchestra’s team and platform will be folded into <a href="https://openai.com/rosalind/" target="_blank" rel="nofollow external noopener" class="sc-adb616fe-0 dJryYS">>Rosalind</a>, OpenAI’s family of AI models and tools for biologists and chemists. The financial terms were not disclosed. Getting a new medicine from first idea to U.S. approval takes time—up to 15 years according to OpenAI. Every month shaved off that timeline is a month earlier that a new treatment can reach the people waiting for it, and a month earlier that the company can generate cash. The process is also absurdly expensive: bringing one approved drug to market can cost more than <a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12668846/" target="_blank" rel="nofollow external noopener" class="sc-adb616fe-0 dJryYS">>$2.6 billion</a>, and <a href="https://arxiv.org/pdf/2106.05386" target="_blank" class="sc-adb616fe-0 dJryYS" rel="nofollow">fewer than 10%</a> of candidates that enter human testing ever make it to pharmacy shelves. Beyond the science itself, OpenAI says drug teams have to coordinate work across internal departments and outside partners, often relying on systems that don’t talk to each other. Those partners usually include contract research organizations, the outside labs hired to run studies, and contract manufacturers that produce the experimental drug. Orchestra’s AI agents—software that can watch over tasks and flag problems on its own—work out which activities and deadlines take the hit, gather the relevant information and compare ways to respond, while scientists and program leaders make the final call. Founded in the fall of 2022, Orchestra raised its <a href="https://jobs.8vc.com/companies/orchestra/jobs/28818089-senior-software-engineer" target="_blank" rel="nofollow external noopener" class="sc-adb616fe-0 dJryYS">>seed round</a> from Andreessen Horowitz, Definition Capital, Insight Partners, and 8VC, and about $20 million in total, according to <a href="https://www.caplight.com/company/orchestra-bio" target="_blank" class="sc-adb616fe-0 dJryYS" rel="nofollow">Caplight data</a>. The company should not be confused with Orchestra BioMed, an unrelated Nasdaq-listed medical device maker that trades under the ticker OBIO. In April, OpenAI launched <a href="https://decrypt.co/364783/openai-gpt-rosalind-drug-discovery-life-sciences-model" target="_blank" class="sc-adb616fe-0 dJryYS" rel="nofollow">GPT-Rosalind</a>, a model built specifically for biology and dru
Grayscale allows investors to deliver Bitcoin in exchange for spot ETF shares.
Cointime news: Grayscale allows investors to obtain shares of its spot ETF by delivering Bitcoin.
AI writes code too fast for testing to keep up: Blacksmith raises $66 million at a $1 billion valuation.
According to CoinWorld news, AI code testing company Blacksmith has announced the completion of a $66 million Series C funding round, led by Sequoia Capital, reaching a valuation of $1 billion. The company was founded in 2024, and when it completed its Series B funding round in March of this year, its valuation was only $550 million. Blacksmith specializes in tools that help developers quickly handle compilation and testing tasks. Since January of this year, the number of code compilation, testing, and other tasks Blacksmith processes weekly has grown from 5 million to over 90 million, an increase of about 18 times. During the same period, the company's annual recurring revenue grew 17 times, with more than 10,000 customers, including Langchain, Granola, and others. Blacksmith says its services can on average double testing speed and reduce costs by 60%. Most of the funding from this round will be used to purchase computing power, with plans to expand computing capacity by at least 5 times by 2027.
The Iranian regime is at its weakest moment in history.
According to CoinWorld news, Israeli Defense Minister Katz: The Iranian regime is at its weakest moment in history, and we realize that this weakness may prompt it to take the most extreme actions, even launching an attack on Israel. If Iran attacks Israel, Iran will be engulfed in fire.
XRP will power Ripple founder's new AI stack.
CoinWorld news: Yellow Network, a blockchain project backed by Ripple's founder, has announced the launch of a technology aimed at enabling instant settlement between autonomous AI programs. The XRP token will become the fundamental settlement mechanism for this new "ultimate" AI stack, combining Yellow's high-speed channels with the capabilities of the XRP Ledger (XRPL) network. The software allows bots to transact within the system without fees and instantly records final settlement on the XRP blockchain. XRPL transfers take only 3-5 seconds and cost very little, making it suitable for AI trading needs.
NVIDIA and Agile Robots launch humanoid robot platform Agile ONE SN, planned for market launch in 2027.
BiJie Network News: NVIDIA has partnered with Agile Robots to launch the Agile ONE SN, a humanoid robot reference platform, with plans to bring it to market in early 2027. According to ITHome, Agile Robots plans to collaborate with NVIDIA to produce up to 2,000 humanoid robots, targeting customers such as universities and corporate research laboratories.
CyberCartel uses Anthropic and SpaceX models to attack Latin American financial institutions.
According to CoinWorld news, the hacker group CyberCartel used AI agents powered by large models such as Anthropic and SpaceX to launch automated attacks on more than 400 financial institutions in Latin America. The AI agents used by the group can autonomously steal passwords and customer data and access bank accounts.
A whale swapped $7.5 million in BTC for 3,038.73 ETH across three addresses.
According to data from Bijie.com: On-chain analyst AI Yi stated that after a five-day hiatus, the position-switching mode has been restarted. Over the past hour, a certain whale swapped $7.5 million worth of BTC for 3,038.73 ETH through three addresses. Since October 11, the cumulative position switching has exceeded 46,103.3 ETH, amounting to over $115 million, with an average switching price of $2,513.11.
Anthropic may publicly file for IPO on Friday.
According to a report by Yahoo Finance, Anthropic may publicly file its IPO application on Friday. Sources say this move would make its listing the largest IPO, potentially surpassing SpaceX's June listing, and serve as a major test of investor demand for AI.
ElevenLabs packages voice agents: supports over 90 languages and is compatible with the OpenAI API.
CoinWorld news: ElevenLabs has released a real-time voice model called eleven realtime, available in two versions: mini and max. The mini version focuses on low-cost conversation, while the max version is aimed at customer service and complex tasks that require continuous tool calls. Both support more than 90 languages and over 17,000 voice options. In Artificial Analysis's 1,000 voice reasoning questions, max achieved an accuracy of 98.8% and began speaking in an average of 0.57 seconds. On the same leaderboard, qwen audio 3.0 realtime plus had a slightly higher accuracy of 99.2%, but took an average of 1.54 seconds to start speaking. The new model has begun rolling out through elevenagents and the realtime api and is being gradually opened up; the api is compatible with OpenAI's websocket protocol, so developers can reuse existing sdks. Projects using webrtc will need to adjust their connection method first.