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More →OpenAI Buys Orchestra Bio to Put AI Agents in Charge of Drug Development Grunt Work
OpenAI has bought Orchestra Bio, a San Francisco startup whose AI agents help drug companies keep sprawling development programs on schedule, the ChatGPT maker <a href="https://openai.com/index/openai-to-acquire-orchestra-bio/" target="_blank" rel="nofollow external noopener" class="sc-adb616fe-0 dJryYS">>announced Tuesday</a>. “Our goal is to help scientists make discoveries and manage the work needed to turn them into treatments that reach patients sooner,” OpenAI said in the announcement. Orchestra’s team and platform will be folded into <a href="https://openai.com/rosalind/" target="_blank" rel="nofollow external noopener" class="sc-adb616fe-0 dJryYS">>Rosalind</a>, OpenAI’s family of AI models and tools for biologists and chemists. The financial terms were not disclosed. Getting a new medicine from first idea to U.S. approval takes time—up to 15 years according to OpenAI. Every month shaved off that timeline is a month earlier that a new treatment can reach the people waiting for it, and a month earlier that the company can generate cash. The process is also absurdly expensive: bringing one approved drug to market can cost more than <a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12668846/" target="_blank" rel="nofollow external noopener" class="sc-adb616fe-0 dJryYS">>$2.6 billion</a>, and <a href="https://arxiv.org/pdf/2106.05386" target="_blank" class="sc-adb616fe-0 dJryYS" rel="nofollow">fewer than 10%</a> of candidates that enter human testing ever make it to pharmacy shelves. Beyond the science itself, OpenAI says drug teams have to coordinate work across internal departments and outside partners, often relying on systems that don’t talk to each other. Those partners usually include contract research organizations, the outside labs hired to run studies, and contract manufacturers that produce the experimental drug. Orchestra’s AI agents—software that can watch over tasks and flag problems on its own—work out which activities and deadlines take the hit, gather the relevant information and compare ways to respond, while scientists and program leaders make the final call. Founded in the fall of 2022, Orchestra raised its <a href="https://jobs.8vc.com/companies/orchestra/jobs/28818089-senior-software-engineer" target="_blank" rel="nofollow external noopener" class="sc-adb616fe-0 dJryYS">>seed round</a> from Andreessen Horowitz, Definition Capital, Insight Partners, and 8VC, and about $20 million in total, according to <a href="https://www.caplight.com/company/orchestra-bio" target="_blank" class="sc-adb616fe-0 dJryYS" rel="nofollow">Caplight data</a>. The company should not be confused with Orchestra BioMed, an unrelated Nasdaq-listed medical device maker that trades under the ticker OBIO. In April, OpenAI launched <a href="https://decrypt.co/364783/openai-gpt-rosalind-drug-discovery-life-sciences-model" target="_blank" class="sc-adb616fe-0 dJryYS" rel="nofollow">GPT-Rosalind</a>, a model built specifically for biology and dru
Colombian cryptocurrency broker sentenced to 13 years in prison for money laundering
CoinWorld news: The U.S. Attorney's Office for the Southern District of New York announced that Colombian cryptocurrency broker Leonardo de Jesus Zuluaga Duque was sentenced to 160 months (13 years and 4 months) in prison for his involvement in an international cryptocurrency money laundering and drug trafficking scheme, and was ordered to forfeit approximately $14.75 million and the tokens in four crypto addresses under his control. From May to November 2023, he conspired with others to launder approximately $14.5 million in drug trafficking proceeds using USDT, U.S. shell companies, and an illegal money transmission business, and participated in planning the smuggling of cocaine into the United States.
OpenAI discovered a PHP vulnerability that took down government websites in multiple countries.
CoinWorld news, Decrypt reports, OpenAI's AI discovered two PHP vulnerabilities that caused government websites in countries including Finland, the Netherlands, and France to go offline on Wednesday. OpenAI President Greg Brockman stated that over the past two months they led a coalition aimed at mitigating this severe open-source software vulnerability, php2shell. The vulnerability allows anyone to execute their own code on servers running PHP. PHP released a fix within one day after the vulnerability details leaked. Brockman revealed that the vulnerability had existed in PHP for 14 years, and the limited version that appeared in 2024 was not considered a major issue at the time. OpenAI has also pledged $1 billion for its AI project to protect critical infrastructure.
Most memecoins die within a day: MemeToro's AI launchpad solution
BiJie Network data: MemeToro has launched an AI memecoin launchpad on the BNB Chain, adopting fixed-price financing and escrow contracts, and proposing a different launch process. Bitquery data shows that of nearly nine million pump.fun tokens, 79% were traded only on the first day. The platform plans to publish the reasons for creating tokens before raising funds, and proposes equal-price contributions and contract-controlled financing methods. MemeToro's tokenomics allocates 71% of the 1.2 billion supply to the public sale and 2% to the team. The project's MT presale has reached stage 9, with a price of $0.00649 per token.
Coinbase midterm election Dashboard is now live, available only within the U.S. app.
Coinbase posted on X that its midterm election Dashboard is now live, available only within the Coinbase app in the United States, excluding Michigan and Nevada. The related futures and swaps products are offered by Coinbase Financial Markets, a member of the CFTC and NFA. Trading may result in total loss, the content does not constitute investment advice, and payouts depend on the specific event.
Canadian publisher says Thelyson Orelien used AI to create award-winning book, ends partnership
CoinWorld news: A Canadian publisher stated that Thelyson Orelien used artificial intelligence to create an award-winning book and consequently ended its partnership with him.
Bitcoin's market cap dominance stands at 59.58%.
CoinWorld data: Under CoinWorld's unified market methodology, Bitcoin's market capitalization accounts for 59.58% of the total cryptocurrency market capitalization.
The U.S. Embassy has issued a security alert regarding the Houthi attack on Saudi Arabia.
CoinWorld news: The U.S. Embassy issued a security alert regarding Houthi attacks on Saudi Arabia.
Bitcoin research lead: 1% of global capital invested in Bitcoin would push the price to about $275,000
Bitcoin Magazine reports that Bitcoin's head of research stated that if 1% of global capital were invested in Bitcoin, the price would reach approximately $275,000. He noted that this price represents the lower bound of Bitcoin holdings advocated by large investors such as BlackRock.
PNFP is halted, pending an announcement.
CoinWorld news: PNFP (Pinnacle Financial Partners, Inc.) entered a trading halt at 14:35:15 on October 21, 2026 (Eastern Time), with the official reason listed as pending announcement.